By Raia Hamad
At the age of 20, ‘Posh Spice’ Victoria Beckham was diagnosed with the most common endocrine disorder in women of reproductive age. That endocrine disorder is called Polycystic Ovary Syndrome (PCOS) and it affects 5-10% of women of reproductive age (Knockenhaur et al, 1998). Although it is believed to be immensely under-diagnosed, it is a leading cause of infertility/subfertility. It plagues around 48 million women worldwide and often times this is due to a genetic predisposition — Approximately 50 genes have demonstrated association with PCOS although none are causative of PCOS pathogenesis (Coleman, Tsongalis, 2009). Some of the common symptoms associated with PCOS are amenorrhea (absence of menses), hirsutism (Excess hair on upper lip, midline of lower abdomen, face, etc.), obesity, acne, polycystic appearance of enlarged ovaries, and heavy, painful periods (Azziz et al, 2004).
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